Current Cataract Management Strategies and Therapeutic Approaches in Inherited Retinal Diseases Other Than Retinitis Pigmentosa and Stargardt Disease

Hereditary retinal diseases (HRD) are characterized by genetic, progressive, and often childhood-onset retinal degenerations. HRDs other than retinitis pigmentosa (RP) and Stargardt disease include subtypes such as Leber congenital amaurosis, cone-rod dystrophies, X-linked retinoschisis, and choroideremia. Cataract formation is common in these diseases, especially in the posterior subcapsular type and seen at an early age. The management of cataract in individuals with HRD differs from standard surgical approaches and should be planned in accordance with retinal functions. In this review, cataract development in RP and non-Stargardt HRDs, surgical planning, and interaction with current genetic treatment strategies are evaluated with the literature.