Non-Response to Anti-VEGF in Patients with Wet-Form (Neovascular) AgeRelated Macular Degeneration, Treatment Resistance and Switch of Anti-VEGF Agents

Age-related macular degeneration (AMD) is a chronic and degenerative disease that causes vision loss. Although antivascular endothelial growth factor (Anti-VEGF) drugs are the mainstay of treatment in cases of age-related AMD, there is no similar response to treatment in each patient. In the case of non-response, the treatment approach for the cause must be regulated. Although there is no consensus on the concept of response to treatment, the use of alternative anti-VEGF in cases where drug efficacy is weak is quite common.