Retinal Detachment Related With Hereditary Retinal Diseases; Risk Factors, Pathogenesis and Clinical Management

Hereditary retinal diseases are a group of pathologies characterized by histologically abnormal developing vitreous gel, associated with peripheral retinal degenerative or proliferative changes. In HRD structural alterations in the vitreous with abnormal vitreoretinal adhesions can predispose to developing Retinal Detachment. In many of HRD are presented with a part of syndromes, most of which have systemic abnormalities affecting the joints, skeletal system and cardiovascular system. Due to delayed diagnosis in younger age patient, without prominent symptoms, most of patient with HRD presented with proliferative vitreoretinopathy (PVR) and macula-involving RD.